Document Detail


The Neber route to substituted indoles.
MedLine Citation:
PMID:  16433505     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two complementary procedures have been developed for the conversion of the oximes of alpha-aryl ketones to azirines. On heating, the azirines rearrange smoothly to the corresponding indoles. The overall transformation offers a versatile route to indoles, complementary to the Fischer indole synthesis.
Authors:
Douglass F Taber; Weiwei Tian
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  128     ISSN:  0002-7863     ISO Abbreviation:  J. Am. Chem. Soc.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-01-25     Completed Date:  2006-04-13     Revised Date:  2012-01-17    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1058-9     Citation Subset:  IM    
Affiliation:
Department of Chemistry and Biochemistry, University of Delaware, Newark, 19716, USA. taberdf@udel.edu
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MeSH Terms
Descriptor/Qualifier:
Indoles / chemical synthesis*
Ketones / chemistry
Oximes / chemistry
Grant Support
ID/Acronym/Agency:
GM 60287/GM/NIGMS NIH HHS; R01 GM060287-08/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Indoles; 0/Ketones; 0/Oximes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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