| Near-infrared reflectance analysis to evaluate the nitrogen and fat content of human milk in neonatal intensive care units. | |
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MedLine Citation:
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PMID: 18192331 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To validate near-infrared reflectance analysis (NIRA) as a fast, reliable and suitable method for routine evaluation of human milk's nitrogen and fat content. SETTING: One neonatal intensive care unit. PATIENTS: 124 samples of expressed human milk (55 from preterm mothers and 69 from term mothers). INTERVENTION: Measurement of nitrogen and fat content by NIRA and traditional methods (Gerber method for fat and Kjeldahl method for nitrogen). MAIN OUTCOME MEASURES: Agreement between NIRA and traditional methods. Variability in fat and nitrogen content of human milk. RESULTS: A strong agreement was found between the results of traditional methods and NIRA for both fat and nitrogen content (expressed as g/100 g of milk) in term (mean fat content: NIRA = 2.76; Gerber = 2.76; mean nitrogen content: NIRA = 1.88; Kjeldahl = 1.92) and preterm (mean fat content: NIRA = 3.56; Gerber = 3.52; mean nitrogen content: NIRA = 1.91; Kjeldahl = 1.89) mothers' milk. Nitrogen content of the milk samples, measured by NIRA, ranged from 1.18 g/100 g to 2.71 g/100 g of milk in preterm milk and from 1.48 g/100 g to 2.47 g/100 g in term milk; fat content ranged from 1.27 g/100 g to 6.23 g/100 g of milk in preterm milk and from 1.01 g/100 g to 6.01 g/100 g of milk in term milk. CONCLUSION: NIRA can be used as a quick and reliable tool for routine monitoring of macronutrient content of human milk and for devising individualised human milk fortification regimens in the feeding of very premature infants. |
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Authors:
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L Corvaglia; B Battistini; V Paoletti; A Aceti; M G Capretti; G Faldella |
Publication Detail:
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Type: Journal Article Date: 2008-01-11 |
Journal Detail:
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Title: Archives of disease in childhood. Fetal and neonatal edition Volume: 93 ISSN: 1468-2052 ISO Abbreviation: Arch. Dis. Child. Fetal Neonatal Ed. Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-25 Completed Date: 2008-09-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9501297 Medline TA: Arch Dis Child Fetal Neonatal Ed Country: England |
Other Details:
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Languages: eng Pagination: F372-5 Citation Subset: AIM; IM |
Affiliation:
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Istituto Clinico di Pediatria Preventiva e Neonatologia, Policlinico S.Orsola-Malpighi, Università di Bologna, Via Massarenti 11-40138 Bologna, Italy. luigi.corvaglia@unibo.it |
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| MeSH Terms | |
Descriptor/Qualifier:
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Breast Feeding* Fats / analysis* Female Humans Infant Formula Infant, Newborn Infant, Premature / growth & development* Intensive Care Units, Neonatal Milk, Human / chemistry* Mothers Nitrogen / analysis* Pregnancy Spectrophotometry, Infrared* Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Fats; 7727-37-9/Nitrogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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