Document Detail

Near infrared optical technologies to illuminate the status of the neonatal brain.
MedLine Citation:
PMID:  25055866     Owner:  NLM     Status:  In-Data-Review    
The neurodevelopmental outcome of at-risk infants in the neonatal intensive care unit (NICU) is concerning despite steady improvement in the survival rate of these infants. Our current management is often complicated by delayed realization of cerebral deficits due to late manifestation and lack of effective screening tools and neuroimaging/monitoring techniques that are suitable for sick neonates at the bedside. Near infrared specstrocopy (NIRS) is a noninvasive, safe, and portable technique providing a wide range of cerebral hemodynamic contrasts for evaluating the brain. The current state of NIRS technology can be devided into three generations. The first generation represents conventional trend monitoring oximeters that are currently the most widely used in the clinical settings, while the second generation focuses on improving the quantitive accuracy of NIRS measurements by advanced optical techniques. The emergence of diffuse optical imaging (DOI) represents a third generation which opens up more potential clinical applications by providing regional comparisons of brain oximetry and functions either at rest or in response to interventions. Successful integration of NIRS/DOI into the clinical setting requires matching the different capabilities of each instrument to specific clinical goals.
Steve M Liao; Joseph P Culver
Related Documents :
9240516 - Deaths related to iodinated contrast media reported spontaneously to the u.s. food and ...
8816046 - Undertakers' death anxiety.
21133966 - Does in utero exposure to synthetic glucocorticoids influence birthweight, head circumf...
16704816 - 1951 influenza epidemic, england and wales, canada, and the united states.
4415846 - Space perception in early infancy: perception within a common auditory-visual space?
228236 - Effect of sleep state on chest distortion and on the ventilatory response to co2 in neo...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current pediatric reviews     Volume:  10     ISSN:  1875-6336     ISO Abbreviation:  Curr Pediatr Rev     Publication Date:  2014  
Date Detail:
Created Date:  2014-07-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101240290     Medline TA:  Curr Pediatr Rev     Country:  United Arab Emirates    
Other Details:
Languages:  eng     Pagination:  73-86     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Neurobehavioral evaluation in the preterm and term infant.
Next Document:  SMN regulates axonal local translation via miR-183/mTOR pathway.