Document Detail

Near fatal hemolysis following repair of ostium primum atrial septal defect.
MedLine Citation:
PMID:  627596     Owner:  NLM     Status:  MEDLINE    
A 15 month old black male who developed near fatal intravascular hemolysis two days after repair of an ostium primum septal defect with a teflon patch is presented. One month after initial operation, reoperation was required for control of hemolysis. At that time a piece of pericardium was placed over the underendothelialized left atrial side of the patch and the mitral cleft was repaired. He initially did well but within several days developed mitral regurgitation. Hemolysis recurred two months postoperatively, but then spontaneously subsided. We propose that the recurrent mitral insufficiency created a defect in the pericardial patch and that caused recurrent hemolysis. Normal endothelial ingrowth probably covered this small defect and hemolysis subsided. Following the second hemolytic episode six months ago, the patient continues to do well.
G L Hines; T T Finnerty; E Doyle; O W Isom
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  19     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:    1978 Jan-Feb
Date Detail:
Created Date:  1978-04-26     Completed Date:  1978-04-26     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  7-10     Citation Subset:  IM    
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MeSH Terms
Anemia, Hemolytic / etiology*
Heart Septal Defects, Atrial / surgery*
Mitral Valve Insufficiency / complications
Pericardium / transplantation
Postoperative Complications
Transplantation, Autologous

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