Document Detail

MedLine Citation:
PMID:  11932007     Owner:  NLM     Status:  MEDLINE    
The inability of current technology to determine contiguous sequence for highly repetitive regions means that centromeres fall within multi-megabase gaps, analogous to black holes from which no information escapes. However, high-resolution mapping of a human X-centromere border reveals a remarkable structure, including a gradient of alpha-satellite divergence up to the edge of the youngest and most homogeneous repeats.
Steven Henikoff
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Publication Detail:
Type:  News    
Journal Detail:
Title:  Trends in genetics : TIG     Volume:  18     ISSN:  0168-9525     ISO Abbreviation:  Trends Genet.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-04-04     Completed Date:  2002-10-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8507085     Medline TA:  Trends Genet     Country:  England    
Other Details:
Languages:  eng     Pagination:  165-7     Citation Subset:  IM    
Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.
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MeSH Terms
DNA Transposable Elements
DNA, Satellite / genetics
Euchromatin / genetics
Evolution, Molecular
Repetitive Sequences, Nucleic Acid
Sequence Analysis, DNA
X Chromosome*
Reg. No./Substance:
0/DNA Transposable Elements; 0/DNA, Satellite; 0/Euchromatin; 0/Heterochromatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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