Document Detail


Near infrared spectroscopy for the detection of desaturations in vulnerable ischemic brain tissue: a pilot study at the stroke unit bedside.
MedLine Citation:
PMID:  22198984     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: There is uncertainty whether bilateral near infrared spectroscopy (NIRS) can be used for monitoring of patients with acute stroke.
METHODS: The NIRS responsiveness to systemic and stroke-related changes was studied overnight by assessing the effects of brief peripheral arterial oxygenation and mean arterial pressure alterations in the affected versus nonaffected hemisphere in 9 patients with acute stroke.
RESULTS: Significantly more NIRS drops were registered in the affected compared with the nonaffected hemisphere (477 drops versus 184, P<0.001). In the affected hemispheres, nearly all peripheral arterial oxygenation drops (n=128; 96%) were detected by NIRS; in the nonaffected hemispheres only 23% (n=30; P=0.17). Only a few mean arterial pressure drops were followed by a significant NIRS drop. This was however significantly different between both hemispheres (32% versus 13%, P=0.01).
CONCLUSIONS: This pilot study found good responsiveness of NIRS signal to systemic and stroke-related changes at the bedside but requires confirmation in a larger sample.
Authors:
Marcel J H Aries; Adriaan D Coumou; Jan Willem J Elting; Joep J van der Harst; Berry P H Kremer; Patrick C A J Vroomen
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-12-22
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  43     ISSN:  1524-4628     ISO Abbreviation:  Stroke     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-03-28     Completed Date:  2012-05-22     Revised Date:  2012-08-22    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1134-6     Citation Subset:  IM    
Affiliation:
University Medical Centre Groningen, Department of Neurology, The Netherlands, Hanzeplein 1, 9700 RB Groningen. m.j.h.aries@umcg.nl
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Blood Pressure
Brain / metabolism*,  physiopathology
Brain Ischemia / metabolism*,  physiopathology
Cerebral Arteries / metabolism*,  physiopathology
Female
Humans
Male
Middle Aged
Oxygen / metabolism*
Spectrophotometry, Infrared / methods
Stroke / metabolism*,  physiopathology
Chemical
Reg. No./Substance:
7782-44-7/Oxygen
Comments/Corrections
Comment In:
Stroke. 2012 Jul;43(7):e61; author reply e62   [PMID:  22539547 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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