Document Detail


N(delta)-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-l-ornithine, a novel methylglyoxal-arginine modification in beer.
MedLine Citation:
PMID:  11170600     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
N(delta)-(5-Hydroxy-4,6-dimethylpyrimidine-2-yl)-L-ornithine, or Argpyrimidine, was identified and quantified in beer by high-performance liquid chromatography (HPLC) and coupled gas chromatography-mass spectrometry (HRGC-MS). This novel fluorescent arginine Maillard modification represents the first amino acid modification reported in beer retaining the full backbone of the original amino acid. Two mechanisms of formation could be verified: the major pathway via methylglyoxal and the minor pathway via 5-deoxypentoses. Argpyrimidine concentrations, determined in 35 lager-type beer varieties, reached up to 27 nmol/L and could be positively correlated to beer color and wort content. Within this context, 5-deoxy-D-ribose was identified as a novel intermediate of the Maillard reaction of maltose by HRGC-MS and independent synthesis.
Authors:
M A Glomb; D Rösch; R H Nagaraj
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  49     ISSN:  0021-8561     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-06-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  366-72     Citation Subset:  IM    
Affiliation:
Institute of Food Chemistry, Technical University of Berlin, Gustav-Meyer-Allee 25, TIB4/3-1, 13355 Berlin, Germany. glom1530@mailszrz.zrz.tu-berlin.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acetone / analogs & derivatives*,  chemistry
Aldehydes / chemistry
Beer / analysis*
Chromatography, High Pressure Liquid
Color
Deoxyribose / analysis
Gas Chromatography-Mass Spectrometry
Maillard Reaction
Ornithine / analogs & derivatives,  analysis*,  chemical synthesis
Pyrimidines / analysis*,  chemical synthesis
Pyruvaldehyde / chemistry
Chemical
Reg. No./Substance:
0/Aldehydes; 0/Pyrimidines; 0/argpyrimidine; 116-09-6/acetol; 533-67-5/Deoxyribose; 67-64-1/Acetone; 7006-33-9/Ornithine; 78-98-8/Pyruvaldehyde

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Structure and dynamics of high molecular weight glutenin subunits of durum wheat (Triticum durum) in...
Next Document:  Low-temperature brewing by freeze-dried immobilized cells on gluten pellets.