| Nausea and vomiting of pregnancy: what about quality of life? | |
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MedLine Citation:
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PMID: 18752585 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of this study was to determine the impact of nausea and vomiting of pregnancy (NVP) and other determinants on generic and NVP-specific health-related quality of life (QOL) in the first trimester of pregnancy. DESIGN: Prospective study. SETTING: Centre Hospitalier Universitaire (CHU) Sainte-Justine or René-Laennec clinics, Montreal, Quebec, Canada. POPULATION: Pregnant women attending the clinics for their prenatal care from 2004 to 2006. Women were eligible if they were > or =18 years of age and < or =16 weeks of gestation at the time of their first prenatal visit. METHODS: After their first prenatal visit, women were asked to fill out a questionnaire covering maternal characteristics, presence and severity of NVP, and health-related QOL. MAIN OUTCOME MEASURES: QOL was measured by the generic 12-item Short Form Health Survey v.1 (SF-12) and the NVP-specific Quality of Life for Nausea and Vomiting during Pregnancy. RESULTS: Of the 367 pregnant women included in the study, 78.5% of women reported NVP in the first trimester of pregnancy. Multivariable linear models showed that presence of NVP in the first trimester of pregnancy was significantly associated with a lower physical component summary scale (P < 0.0001) and mental component summary scale (P = 0.0066) of the SF-12 scores. More severe NVP (moderate versus mild: P = 0.0002; severe versus mild: P = 0.0177 as measured by the validated modified Pregnancy-Unique Quantification of Emesis and Nausea index), intensity of nausea symptoms reported on a visual analogue scale (P < 0.0001), and nonpharmacological methods used to ease NVP symptoms in the first trimester of pregnancy (P = 0.0059) were significantly associated with poorer NVP-specific QOL among women suffering from NVP. CONCLUSION: These findings show that presence and severity of NVP have a negative impact on health-related QOL, which emphasises the importance of an optimal management of NVP. |
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Authors:
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A Lacasse; E Rey; E Ferreira; C Morin; A Bérard |
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Publication Detail:
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Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't Date: 2008-08-25 |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 115 ISSN: 1471-0528 ISO Abbreviation: BJOG Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-27 Completed Date: 2009-01-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 1484-93 Citation Subset: AIM; IM |
Affiliation:
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Faculty of Pharmacy, University of Montreal, Montreal, Quebec, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Health Status Humans Life Style Maternal Age Morning Sickness / psychology*, therapy Parity Pregnancy Pregnancy Trimester, First Prospective Studies Quality of Life* Quebec Socioeconomic Factors Young Adult |
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