Document Detail

Nausea and vomiting in pregnancy: an association between symptoms and maternal prostaglandin E2.
MedLine Citation:
PMID:  11014944     Owner:  NLM     Status:  MEDLINE    
This study investigated the aetiology of nausea and vomiting in pregnancy (NVP) in primary care using a new methodology. Eighteen women in early pregnancy had 2 blood samples taken in one 24-hour time period, one when they were symptomatic, and another when they were symptom-free. Maternal serum levels of the candidate agents PGE2, IL-1beta, and TNFalpha were measured. The study shows a positive relationship between NVP and maternal serum PGE2 levels in early pregnancy.
R Gadsby; A Barnie-Adshead; D Grammatoppoulos; P Gadsby
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  50     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  2000  
Date Detail:
Created Date:  2000-11-28     Completed Date:  2000-12-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  149-52     Citation Subset:  IM    
Copyright Information:
Copyright 2000 S. Karger AG, Basel
GP Nuneaton and Warwick University, Coventry, UK.
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MeSH Terms
Dinoprostone / blood*
Interleukin-1 / blood
Nausea / blood,  etiology*
Pregnancy Complications / blood*
Pregnancy Trimester, First / blood
Tumor Necrosis Factor-alpha / metabolism
Vomiting / blood,  etiology*
Reg. No./Substance:
0/Interleukin-1; 0/Tumor Necrosis Factor-alpha; 363-24-6/Dinoprostone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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