Document Detail


Nausea and vomiting associate with increasing maternal androgen levels in otherwise uncomplicated pregnancies.
MedLine Citation:
PMID:  12694117     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The objective of the present study was to investigate the hypothesis that maternal androgen levels associate with nausea and vomiting in otherwise uncomplicated pregnancies. METHODS: One hundred and twenty-nine women with uncomplicated pregnancies, reported nausea and vomiting in weeks 17, 25, 33, 37, and when admitted for delivery. Maternal levels of androstenedione, dehydroepiandrosterone sulfate (DHEAS), testosterone, and sex hormone binding globulin (SHBG) were measured and the free testosterone index calculated in weeks 17 and 33 of pregnancy. RESULTS: Maternal levels of androstenedione and DHEAS associated positively with nausea and vomiting in week 17. In week 33, testosterone and DHEAS associated positively with nausea and vomiting, as well as androstenedione. A calculated emesis score associated positively with increasing average levels of both androstenedione and testosterone during pregnancy, as well as the free testosterone index. CONCLUSIONS: Nausea and vomiting associate with increasing maternal androgen levels during otherwise uncomplicated pregnancies. Whether androgens are causally related to emesis gravidarum remains unknown.
Authors:
Sven Magnus Carlsen; Eszter Vanky; Geir Jacobsen
Related Documents :
9286097 - Sublingual plicae (anterior processes) are not necessary for garter snake vomeronasal f...
18160087 - Comparative evaluation of direct agglutination test, rk39 and soluble antigen elisa and...
9365937 - Treatment of gastritis in cheetahs (acinonyx jubatus).
25017687 - Hypersensitivity from intravenous iron products.
12100427 - Antenatal diagnosis of placenta percreta with planned in situ retention and methotrexat...
24527 - Some clinical aspects of caprine reproduction.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  82     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-04-15     Completed Date:  2003-05-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  225-8     Citation Subset:  IM    
Affiliation:
Section of Endocrinology, Department of Medicine, St. Olavs. Hospital, University Hospital of Trondheim, Norway. sven.carlsen@medisin.ntnu.no
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Androgens / blood*
Androstenedione / blood
Dehydroepiandrosterone Sulfate / blood
Female
Humans
Infant, Newborn
Nausea / blood*
Pregnancy
Pregnancy Complications / blood*
Sex Hormone-Binding Globulin / metabolism
Testosterone / blood
Vomiting / blood*
Grant Support
ID/Acronym/Agency:
1-HD-4-2803/HD/NICHD NIH HHS
Chemical
Reg. No./Substance:
0/Androgens; 0/Sex Hormone-Binding Globulin; 58-22-0/Testosterone; 63-05-8/Androstenedione; 651-48-9/Dehydroepiandrosterone Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Histopathological changes in ovary and endometrium after tubal ligation: a rat model.
Next Document:  Prospective study of mother-to-infant transmission of hepatitis C virus: a 10-year survey (1990-2000...