Document Detail


Nausea and vomiting after general anaesthesia with isoflurane, enflurane or fentanyl in combination with nitrous oxide and oxygen.
MedLine Citation:
PMID:  3181147     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One-hundred and eighty patients undergoing elective abdominal hysterectomy were anaesthetized in random order with isoflurane, enflurane or fentanyl in combination with nitrous oxide and oxygen. Incidence and severity of emetic sequelae (none, nausea, retching or vomiting) were studied during the first 24 h after the operation. Patients who received isoflurane had significantly (P less than 0.01) less emetic sequelae (27%) during the first 2 h in the recovery room compared with patients who received enflurane (45%) or fentanyl (48%). There was no difference between the groups in the overall incidence of emetic sequelae during the time period of 2-24 h post-operatively (isoflurane 65%, enflurane 77% and fentanyl 77%). Significantly (P less than 0.02) more patients had emetic sequelae if they had experienced nausea or had vomited after previous anaesthetics.
Authors:
J Hovorka; K Korttila; O Erkola
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  European journal of anaesthesiology     Volume:  5     ISSN:  0265-0215     ISO Abbreviation:  Eur J Anaesthesiol     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-12-01     Completed Date:  1988-12-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8411711     Medline TA:  Eur J Anaesthesiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  177-82     Citation Subset:  IM    
Affiliation:
Department of Anaesthesia, Helsinki University Central Hospital, Finland.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia, Inhalation*
Enflurane / adverse effects*
Female
Fentanyl / adverse effects*
Humans
Hysterectomy
Isoflurane / adverse effects*
Middle Aged
Nausea / chemically induced*
Nitrous Oxide
Oxygen
Random Allocation
Vomiting / chemically induced*
Chemical
Reg. No./Substance:
10024-97-2/Nitrous Oxide; 13838-16-9/Enflurane; 26675-46-7/Isoflurane; 437-38-7/Fentanyl; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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