Document Detail

Nausea, emesis, and muscle weakness in a pregnant adolescent.
MedLine Citation:
PMID:  16449157     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Gitelman syndrome is a rare autosomal recessive disorder that presents in early adulthood with fatigue, muscle cramps and electrolyte abnormalities. CASE: A 17-year-old African-American woman presented at 17 weeks of pregnancy with nausea, emesis, profound lower extremity proximal muscle weakness, hypokalemia, and hypomagnesemia. After a thorough evaluation, Gitelman syndrome was diagnosed. The patient was maintained on high levels of potassium and magnesium supplementation throughout the rest of her pregnancy and delivered a healthy infant. CONCLUSION: In pregnancy, nausea and emesis is most commonly attributed to hyperemesis gravidarum. However, an atypical presentation of these symptoms and/or the coexistence of less common complaints warrant further investigation.
Sindhu K Srinivas; Sabrina Sukhan; Michal A Elovitz
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  107     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-02-01     Completed Date:  2006-04-04     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  481-4     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA.
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MeSH Terms
Alkalosis / diagnosis
Calcium / urine*
Diagnosis, Differential
Hypokalemia / diagnosis
Magnesium Deficiency / diagnosis
Metabolic Diseases / diagnosis*
Muscle Weakness* / etiology
Nausea* / etiology
Pregnancy Complications / diagnosis*
Vomiting* / etiology
Reg. No./Substance:

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