Document Detail

Nature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen.
MedLine Citation:
PMID:  4256063     Owner:  NLM     Status:  MEDLINE    
The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate-proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroitin sulphate and a preparation of soluble collagen, with a partition-equilibrium technique, afforded similar results.
B Obrink; A Wasteson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Biochemical journal     Volume:  121     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1971 Jan 
Date Detail:
Created Date:  1972-01-12     Completed Date:  1972-01-12     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  227-33     Citation Subset:  IM    
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MeSH Terms
Chondroitin / metabolism*
Collagen / metabolism*
Glycoproteins / metabolism*
Glycosaminoglycans / metabolism*
Hydrogen-Ion Concentration
Macromolecular Substances
Protein Binding*
Sulfates / metabolism
Reg. No./Substance:
0/Gels; 0/Glycoproteins; 0/Glycosaminoglycans; 0/Macromolecular Substances; 0/Sulfates; 9004-54-0/Dextrans; 9007-27-6/Chondroitin; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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