Document Detail


Naturally occurring toxic factors in plants and animals used as food.
MedLine Citation:
PMID:  5905948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Toxic components of natural foodstuffs are discussed, with special reference to lathyrogens, pressor amines, azoxyglycosides, and labile sulfur compounds. The osteolathyrogen, gamma-glutamyl-beta-aminopropionitrile, in sweet pea (Lathyrus odoratus) seeds induces skeletal deformities and aortic rupture, probably by interfering with normal maturation of collagen fibres. Neurolathyrism in man may be caused by beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, a neurotoxin recently identified in Lathyrus sativus seeds. Histamine, tyramine, noradrenaline, serotonin and other pressor amines occur in fruits and fermented foods such as bananas, pineapples, cheese and wine. Consumption of such foods by patients taking monoamine oxidase-inhibiting drugs (e.g. tranylcypromine) may produce serious hypertensive crises. Cycad nuts, widely used as human food in tropical and subtropical areas, contain a potent carcinogen, methyl azoxymethanol, which is more or less removed prior to use by leaching in water. Consumption of plants of the onion, cabbage and cress families introduces into the body such toxic chemicals as benzyl cyanide, goitrin and thiocyanates. The lachrymatory substance in onions is propenyl sulfenic acid.
Authors:
F M Strong
Related Documents :
22909188 - Occurrence of furan in commercial processed foods in brazil.
10644018 - Metals and arsenic in eye shadows.
10854128 - Hazard identification and dose response of ingested nickel-soluble salts.
7395748 - An industrial hygiene evaluation of chimney sweeping.
16394118 - Diet synergies and mortality--a population-based case-control study of 32,462 hong kong...
12911778 - A kinetic study in adults with food hypersensitivity assessed as eosinophil activation ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  94     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1966 Mar 
Date Detail:
Created Date:  1966-05-22     Completed Date:  1966-05-22     Revised Date:  2010-06-22    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  568-73     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aminopropionitrile / poisoning
Cyanides / poisoning
Food Analysis
Glycosides / poisoning
Goiter / etiology
Humans
Hypertension / etiology
Lathyrism / etiology
Meat*
Monoamine Oxidase Inhibitors
Plant Poisoning*
Plants, Edible*
Sulfur / poisoning
Sympathomimetics / poisoning
Chemical
Reg. No./Substance:
0/Cyanides; 0/Glycosides; 0/Monoamine Oxidase Inhibitors; 0/Sympathomimetics; 151-18-8/Aminopropionitrile; 7704-34-9/Sulfur

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The state of hemoglobin in sickled erythrocytes.
Next Document:  Food-borne bacterial toxins.