Document Detail

Naturally occurring anti-Salmonella agents.
MedLine Citation:
PMID:  11743758     Owner:  NLM     Status:  MEDLINE    
Polygodial and (2E)-hexenal were found to possess antibacterial activity against Salmonella choleraesuis with the minimum bactericidal concentrations (MBC) of 50 microg/mL (0.17 mM) and 100 microg/mL (0.98 mM), respectively. The time kill curve study showed that these two alpha,beta-unsaturated aldehydes were bactericidal against this food-borne bacterium at any stage of growth. However, they showed different effects on the growth of S. choleraesuis. The combination of polygodial and anethole exhibited strong synergism on their bacteriostatic action but only marginal synergism on their bactericidal action.
I Kubo; K Fujita
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  49     ISSN:  0021-8561     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-17     Completed Date:  2002-02-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5750-4     Citation Subset:  IM    
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720-3112, USA.
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MeSH Terms
Aldehydes / pharmacology*
Anisoles / pharmacology*
Anti-Bacterial Agents / pharmacology*
Flavoring Agents / pharmacology
Food Microbiology
Microbial Sensitivity Tests
Salmonella / drug effects*,  growth & development
Reg. No./Substance:
0/Aldehydes; 0/Anisoles; 0/Anti-Bacterial Agents; 0/Flavoring Agents; 104-46-1/anethole; 66-25-1/n-hexanal

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