Document Detail

Natural and modified history of complete atrioventricular septal defect--a 17 year study.
MedLine Citation:
PMID:  2221969     Owner:  NLM     Status:  MEDLINE    
We reviewed 103 cases of isolated complete atrioventricular septal defect. These cases represented 4.4% of the cases of congenital heart disease diagnosed in our hospital by catheterisation and angiography during 1971-88. Most children (n = 76) had Down's syndrome. Banding of the pulmonary artery was performed in seven cases and complete repair in 67 cases. In the period 1971-82 the complete correction was performed at a mean age of 23 months with a surgical mortality of 88.8%. In the period 1983-8 the mean age at complete correction was 13 months, the mortality 43.2%, and the five year actuarial survival was 46.8%. The 22 patients that survived after complete correction were in functional classes I and II of the New York Heart Association classification. After a mean follow up of 10 years only eight (36%) of the 22 who were followed up and treated medically survived; all had developed pulmonary vascular obstructive disease and were in functional classes III or IV. Our findings stress the importance of early complete surgical repair.
P Frontera-Izquierdo; G Cabezuelo-Huerta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  65     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1990 Sep 
Date Detail:
Created Date:  1990-11-07     Completed Date:  1990-11-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  964-6; discussion 966-7     Citation Subset:  AIM; IM    
Department of Paediatrics, Hospital Infantil Universitario La Fe, Valencia, Spain.
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MeSH Terms
Endocardial Cushion Defects / epidemiology,  mortality,  surgery*
Heart Septum / surgery*
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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