Document Detail

Natural history of a visceral leishmaniasis outbreak in highland Ethiopia.
MedLine Citation:
PMID:  19706898     Owner:  NLM     Status:  MEDLINE    
In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records of VL patients treated from May 25, 2005 to December 13, 2007 by the only VL treatment center in the area, maintained by Médecins Sans Frontières-Ethiopia, Operational Center Barcelona-Athens. The median age was 18 years; 77.6% were male. The overall case fatality rate was 4%, but adults 45 years or older were five times as likely to die as 5-29 year olds. Other factors associated with increased mortality included HIV infection, edema, severe malnutrition, pneumonia, tuberculosis, and vomiting. The VL epidemic expanded rapidly over a several-year period, culminating in an epidemic peak in the last third of 2005, spread over two districts, and transformed into a sustained endemic situation by 2007.
Mercè Herrero; Giannos Orfanos; Daniel Argaw; Abate Mulugeta; Pilar Aparicio; Fernando Parreño; Oscar Bernal; Daniel Rubens; Jaime Pedraza; Maria Angeles Lima; Laurence Flevaud; Pedro Pablo Palma; Seife Bashaye; Jorge Alvar; Caryn Bern
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  81     ISSN:  1476-1645     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2009 Sep 
Date Detail:
Created Date:  2009-08-26     Completed Date:  2009-09-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  373-7     Citation Subset:  AIM; IM    
Disease Prevention and Control Programmes, World Health Organization, Addis Ababa, Ethiopia.
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MeSH Terms
Child, Preschool
Disease Outbreaks*
Ethiopia / epidemiology
Leishmaniasis, Visceral / epidemiology*,  mortality
Middle Aged
Retrospective Studies
Risk Factors
Young Adult

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