| Natural history of portal hypertension. | |
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MedLine Citation:
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PMID: 15562666 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A rise in pressure in the portal vein is a frequent occurrence in patients with cirrhosis. One common manifestation affecting at least 50% of cirrhosis patients is the development of gastroesophageal varices and portal hypertensive gastropathy. Bleeding from gastric or esophageal varices will occur in approximately 1/4 of cirrhotic patients with an associated high mortality. Large esophageal varices that have red color signs and isolated gastric varices in the fundus of the stomach are most likely to hemorrhage. The greatest risk of bleeding is during the first year following the index endoscopy. Once varices have bled they are almost certain to rebleed in the absence of therapy. Similarly, severe portal hypertensive gastropathy is likely to cause chronic blood loss. Knowledge of the natural history of gastroesophageal varices allows for the development of effective treatment strategies. |
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Authors:
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T D Boyer |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Clinics in liver disease Volume: 1 ISSN: 1089-3261 ISO Abbreviation: Clin Liver Dis Publication Date: 1997 May |
Date Detail:
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Created Date: 2004-11-25 Completed Date: 2005-02-08 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 9710002 Medline TA: Clin Liver Dis Country: United States |
Other Details:
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Languages: eng Pagination: 31-44, x Citation Subset: IM |
Affiliation:
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Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia 30322, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Esophageal and Gastric Varices
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etiology* Gastrointestinal Hemorrhage / etiology Humans Liver Cirrhosis / complications Recurrence Risk Factors Severity of Illness Index |
| Grant Support | |
ID/Acronym/Agency:
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DK50680/DK/NIDDK NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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