Document Detail

Natural history of pelviureteric obstruction detected by prenatal sonography.
MedLine Citation:
PMID:  2178725     Owner:  NLM     Status:  MEDLINE    
Fifty-six infants with prenatally diagnosed hydronephrosis are reported. In all instances the diagnosis was confirmed postnatally and at renography 45 were obstructed; 38 obstructed kidneys (84%) and all of the non-obstructed kidneys had a differential function exceeding 40% of total function. Latterly we have come to recommend early pyeloplasty only if differential function of a renographically obstructed kidney is less than 40%; 6 early pyeloplasties were performed for this reason; 28 infants (30 renal units) were managed non-operatively and 18 of these (19 renal units) were reassessed renographically. In 11 the obstruction persists. Sonography demonstrated improving hydronephrosis in 8 kidneys with resolution in 5 and no change in 6. Of the other 10 infants (11 renal units), the hydronephrosis has improved in 4, resolved in 1 and remains unchanged in 6. Our experience suggests that neonatal and early pyeloplasty can be restricted to a modest number of infants in whom there is impaired renal function. In cases with normal function the natural history appears essentially benign and does not justify routine pyeloplasty.
A J Arnold; A M Rickwood
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of urology     Volume:  65     ISSN:  0007-1331     ISO Abbreviation:  Br J Urol     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-04-23     Completed Date:  1990-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15740090R     Medline TA:  Br J Urol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  91-6     Citation Subset:  IM    
Department of Paediatric Urology, Royal Liverpool Children's Hospital.
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MeSH Terms
Fetal Diseases / diagnosis*
Hydronephrosis / diagnosis,  etiology
Infant, Newborn
Kidney Pelvis / pathology*
Prenatal Diagnosis*
Ureteral Obstruction / complications,  diagnosis*

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