Document Detail


Natural history and patterns of current practice in heart failure. The Studies of Left Ventricular Dysfunction (SOLVD) Investigators.
MedLine Citation:
PMID:  8376685     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A total of 6,273 consecutive relatively unselected patients with heart failure or left ventricular dysfunction, or both (mean age 62 +/- 12 years, mean ejection fraction 31 +/- 9%), were enrolled in the Studies of Left Ventricular Dysfunction (SOLVD) Registry over a period of 14 months. All patients were followed up for vital status and hospital admissions at 1 year. Ischemic heart disease was the underlying cause of failure or dysfunction in approximately 70% of patients, whereas hypertensive heart disease was considered to be primarily involved in only 7%. There were striking differences in the etiology of heart failure among blacks and whites: 73% of whites had an ischemic etiology of failure versus only 36% of blacks; 32% of blacks had a hypertensive condition versus only 4% of whites. The total 1-year mortality rate was 18%; 19% of patients had hospital admissions for heart failure and 27% either died or had a hospital admission for congestive heart failure during the 1st year of follow-up. Factors related to 1-year mortality or hospital admission for congestive heart failure included age, ejection fraction, diabetes mellitus, atrial fibrillation and female gender. There was no difference in mortality associated with congestive heart failure among blacks and whites, but hospital admissions for heart failure were more frequent in blacks. Digitalis and diuretic agents were the drugs most often used in these patients, who were often taking many medications in relation to severity of congestive heart failure symptoms and ejection fraction.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
M G Bourassa; O Gurné; S I Bangdiwala; J K Ghali; J B Young; M Rousseau; D E Johnstone; S Yusuf
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  22     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-10-20     Completed Date:  1993-10-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  14A-19A     Citation Subset:  AIM; IM    
Affiliation:
Montreal Heart Institute, Montreal, Quebec, Canada.
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Aged
Belgium / epidemiology
Canada / epidemiology
Chi-Square Distribution
Continental Population Groups
Female
Follow-Up Studies
Heart Failure / diagnosis*,  drug therapy,  mortality
Humans
Male
Middle Aged
Odds Ratio
Physician's Practice Patterns* / statistics & numerical data
Registries / statistics & numerical data
Risk Factors
Sex Factors
United States / epidemiology
Ventricular Function, Left*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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