Document Detail

Natural history and patterns of current practice in heart failure. The Studies of Left Ventricular Dysfunction (SOLVD) Investigators.
MedLine Citation:
PMID:  8376685     Owner:  NLM     Status:  MEDLINE    
A total of 6,273 consecutive relatively unselected patients with heart failure or left ventricular dysfunction, or both (mean age 62 +/- 12 years, mean ejection fraction 31 +/- 9%), were enrolled in the Studies of Left Ventricular Dysfunction (SOLVD) Registry over a period of 14 months. All patients were followed up for vital status and hospital admissions at 1 year. Ischemic heart disease was the underlying cause of failure or dysfunction in approximately 70% of patients, whereas hypertensive heart disease was considered to be primarily involved in only 7%. There were striking differences in the etiology of heart failure among blacks and whites: 73% of whites had an ischemic etiology of failure versus only 36% of blacks; 32% of blacks had a hypertensive condition versus only 4% of whites. The total 1-year mortality rate was 18%; 19% of patients had hospital admissions for heart failure and 27% either died or had a hospital admission for congestive heart failure during the 1st year of follow-up. Factors related to 1-year mortality or hospital admission for congestive heart failure included age, ejection fraction, diabetes mellitus, atrial fibrillation and female gender. There was no difference in mortality associated with congestive heart failure among blacks and whites, but hospital admissions for heart failure were more frequent in blacks. Digitalis and diuretic agents were the drugs most often used in these patients, who were often taking many medications in relation to severity of congestive heart failure symptoms and ejection fraction.(ABSTRACT TRUNCATED AT 250 WORDS)
M G Bourassa; O Gurné; S I Bangdiwala; J K Ghali; J B Young; M Rousseau; D E Johnstone; S Yusuf
Related Documents :
17203795 - Cardiovascular disease in hiv infection.
3347445 - The benefit of cesarean section in acute myocardial infarction complicated by premature...
17552085 - Treating hyponatremia in heart failure.
7649665 - Salutary effect of terminalia arjuna in patients with severe refractory heart failure.
23403495 - Mechanistic, technical, and clinical perspectives in therapeutic stimulation of coronar...
12943045 - Transient cardiac dysfunction and pulmonary edema in exertional heat stroke.
Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  22     ISSN:  0735-1097     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-10-20     Completed Date:  1993-10-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  14A-19A     Citation Subset:  AIM; IM    
Montreal Heart Institute, Montreal, Quebec, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Age Factors
Belgium / epidemiology
Canada / epidemiology
Chi-Square Distribution
Continental Population Groups
Follow-Up Studies
Heart Failure / diagnosis*,  drug therapy,  mortality
Middle Aged
Odds Ratio
Physician's Practice Patterns* / statistics & numerical data
Registries / statistics & numerical data
Risk Factors
Sex Factors
United States / epidemiology
Ventricular Function, Left*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Efficacy of vasodilators in the treatment of heart failure.
Next Document:  Comparative neurohormonal responses in patients with preserved and impaired left ventricular ejectio...