Document Detail

Natural history of familial myomas.
MedLine Citation:
PMID:  16188369     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the natural history of myomas in familial cases and to compare the tendencies of myomas between familial and non-familial cases. STUDY DESIGN: Subjects with familial and non-familial myomas were identified from the hospital records and the reliable details of the myomas were collected. RESULTS: In the familial cases there are several myomas, four or more. In the non-familial cases, there is usually only one single myoma, which is bigger than in familial cases. In the familial group, the diagnosis and surgery was made earlier. In the familial group, there were more pregnancies and less infertility problems. CONCLUSION: There is a significant difference in the natural history of the familial and non-familial cases. In familial cases, subjects have four or more myomas while in non-familial cases the fibroid is single and large.
Outi Uimari; Sanna Suomalainen-König; Nina Sakkinen; Markku Santala; Pentti Nieminen; Markku Ryynanen
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Publication Detail:
Type:  Journal Article     Date:  2005-09-26
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  125     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-09-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  255-8     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Oulu University Hospital, PL 24, 90029 OYS Oulu, Finland.
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MeSH Terms
Case-Control Studies
Family Health
Leiomyoma / genetics*,  pathology
Middle Aged
Uterine Neoplasms / genetics*,  pathology

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