Document Detail


Natural history of cholelithiasis in patients with alcoholic cirrhosis (cholelithiasis in cirrhotic patients).
MedLine Citation:
PMID:  3827357     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To assess the natural history of cholelithiasis in patients with cirrhosis, 32 charts coded for both diseases were retrospectively reviewed. Cholecystectomy was performed in 22 patients. Only two patients met criteria for acute cholecystitis and two patients had suspected choledocholithiasis. Despite the high incidence of preoperative jaundice (32%), no common duct stones were documented. There was no operative mortality. The complication rate was 45%. In 10 patients not operated upon, two patients died of liver failure and the remaining eight patients are alive 8 months to 13 years after diagnosis (mean: 46 months) with no active biliary disease. It is concluded that: jaundice in this subpopulation most often reflects hepatocellular injury and rarely biliary tract obstruction, there appears to be a much lower incidence of acute cholecystitis and choledocholithiasis in cirrhotic patients with cholelithiasis than in the normal population, and patients with cirrhosis and asymptomatic cholelithiasis can be safely managed without operation.
Authors:
G Dunnington; E Alfrey; R Sampliner; F Kogan; C Putnam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of surgery     Volume:  205     ISSN:  0003-4932     ISO Abbreviation:  Ann. Surg.     Publication Date:  1987 Mar 
Date Detail:
Created Date:  1987-04-03     Completed Date:  1987-04-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372354     Medline TA:  Ann Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  226-9     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Cholecystectomy / adverse effects
Cholelithiasis / complications*,  surgery
Female
Humans
Liver Cirrhosis, Alcoholic / complications*,  surgery
Male
Middle Aged
Retrospective Studies
Comments/Corrections

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