Document Detail


Natural and edible biopolymer poly-gamma-glutamic acid: synthesis, production, and applications.
MedLine Citation:
PMID:  16278834     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Poly-gamma-glutamic acid (gamma-PGA) is a very promising biodegradable polymer that is produced by Bacillus subtilis. Gamma-PGA is water-soluble, anionic, biodegradable, and edible. This paper reviews the production of a strain of gamma-PGA and recent developments with respect to applications in terms of Ca absorption, moisturizing properties, gamma-PGA conjugation, super absorbent polymer, and so on. Our recent research shows that gamma-PGA can be used as an immune-stimulating and anti-tumor agent, especially at high molecular weight.
Authors:
Moon-Hee Sung; Chung Park; Chul-Joong Kim; Haryoung Poo; Kenji Soda; Makoto Ashiuchi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chemical record (New York, N.Y.)     Volume:  5     ISSN:  1527-8999     ISO Abbreviation:  Chem Rec     Publication Date:  2005  
Date Detail:
Created Date:  2005-12-12     Completed Date:  2006-07-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101085550     Medline TA:  Chem Rec     Country:  United States    
Other Details:
Languages:  eng     Pagination:  352-66     Citation Subset:  IM    
Copyright Information:
2005 The Japan Chemical Journal Forum and Wiley Periodicals, Inc.
Affiliation:
Department of Bio & Nanochemistry, Kookmin University, 861-1 Chongnung-dong, Songbuk-gu, Seoul 136-702, Korea. smoonhee@kookmin.ac.kr
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MeSH Terms
Descriptor/Qualifier:
Adjuvants, Immunologic / administration & dosage,  chemical synthesis,  chemistry
Administration, Oral
Animals
Antineoplastic Agents / administration & dosage,  chemical synthesis,  chemistry
Biological Products / administration & dosage,  chemical synthesis*,  chemistry
Biopolymers / administration & dosage,  chemistry*
Humans
Molecular Weight
Polyglutamic Acid / administration & dosage,  analogs & derivatives*,  chemical synthesis,  chemistry
Chemical
Reg. No./Substance:
0/Adjuvants, Immunologic; 0/Antineoplastic Agents; 0/Biological Products; 0/Biopolymers; 0/poly(gamma-glutamic acid); 25513-46-6/Polyglutamic Acid

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