Document Detail


Natural antioxidant compounds in risk factors for CVD.
MedLine Citation:
PMID:  17572098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The benefits of drug treating hypertension, hyperglycemia and hyperlipidemias in terms of reduction of CVD morbidity and mortality are well established. However, there is epidemiological evidence that consumption of certain foods results to a reduction in myocardial infarction markers. Given in many reviews is the impact of dietary antioxidants pertained to LDL oxidation and to vascular endothelial dysfunction. The potential of a diet rich in these compounds on the management of hypertension, hyperglycemia and hyperlipidemias is hereby criticized. Although their clinical use not always translates into clinical benefit, data are motivating. In the future, these agents may be very important complementary treatment options for subjects with high risk for CVD.
Authors:
Andriana C Kaliora; George V Z Dedoussis
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-05-10
Journal Detail:
Title:  Pharmacological research : the official journal of the Italian Pharmacological Society     Volume:  56     ISSN:  1043-6618     ISO Abbreviation:  Pharmacol. Res.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-31     Completed Date:  2007-11-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8907422     Medline TA:  Pharmacol Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  99-109     Citation Subset:  IM    
Affiliation:
Department of Science of Dietetics-Nutrition, Harokopio University of Athens, 70 El. Venizelou Ave., 17671 Athens, Greece. akaliora@hua.gr
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MeSH Terms
Descriptor/Qualifier:
Animals
Antihypertensive Agents / pharmacology,  therapeutic use*
Antilipemic Agents / pharmacology,  therapeutic use*
Antioxidants / pharmacology,  therapeutic use*
Cardiovascular Diseases / etiology,  metabolism,  physiopathology,  prevention & control*
Endothelium, Vascular / drug effects,  physiopathology
Humans
Hyperglycemia / complications,  drug therapy*,  metabolism,  physiopathology
Hyperlipidemias / complications,  drug therapy*,  metabolism,  physiopathology
Hypertension / complications,  drug therapy*,  metabolism,  physiopathology
Hypoglycemic Agents / pharmacology,  therapeutic use*
Oxidative Stress / drug effects
Risk Factors
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antihypertensive Agents; 0/Antilipemic Agents; 0/Antioxidants; 0/Hypoglycemic Agents

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