Document Detail


Natriuretic peptides in the diagnosis and management of heart failure.
MedLine Citation:
PMID:  16966666     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The natriuretic peptides are a family of related hormones that play a crucial role in cardiovascular homeostasis. They have recently emerged as potentially important clinical markers in heart failure. Recent data have suggested an important role for these markers in establishing the diagnosis of heart failure in patients with unexplained dyspnea in both acute care and ambulatory settings. Other clinical uses of the natriuretic peptides, such as screening for asymptomatic ventricular dysfunction, establishing prognosis or guiding titration of drug therapy, are under investigation but have not yet sufficiently been validated for widespread clinical use.
Authors:
G Michael Felker; John W Petersen; Daniel B Mark
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne     Volume:  175     ISSN:  1488-2329     ISO Abbreviation:  CMAJ     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-12     Completed Date:  2006-10-12     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  9711805     Medline TA:  CMAJ     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  611-7     Citation Subset:  AIM; IM    
Affiliation:
Outcomes Research Group, Duke Clinical Research Institute, and the Division of Cardiology and Department of Medicine, Duke University Medical Center, Durham, NC 27705, USA.
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MeSH Terms
Descriptor/Qualifier:
Atrial Natriuretic Factor / blood*,  physiology
Bayes Theorem
Biological Markers / blood*
Dyspnea / blood,  etiology
Heart Failure / complications,  diagnosis*,  physiopathology
Humans
Likelihood Functions
Natriuretic Peptide, Brain / blood*,  physiology
Peptide Fragments / blood
Prognosis
ROC Curve
Reference Values
Sensitivity and Specificity
Treatment Outcome
Ventricular Dysfunction, Left / diagnosis
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Peptide Fragments; 0/pro-brain natriuretic peptide (1-76); 114471-18-0/Natriuretic Peptide, Brain; 85637-73-6/Atrial Natriuretic Factor
Comments/Corrections
Comment In:
CMAJ. 2007 Feb 27;176(5):659   [PMID:  17325337 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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