| Natriuresis induced by cholinergic stimulation of the locus coeruleus in the rat. | |
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MedLine Citation:
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PMID: 2385627 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Carbachol injected into the locus coeruleus (LC) induced a dose-dependent natriuresis in the rat. This natriuresis was maintained above control levels during the 120 min of urine sampling. Seizures and arterial blood pressure increase were also observed but they disappeared within 20 min after carbachol injection. Natriuresis was not obtained with either injections of carbachol outside the LC or with hypertonic solutions injected into the LC. Injection of atropine into the LC blocked the natriuresis induced by carbachol. In summary, our data show that carbachol induces natriuresis by an action on muscarinic receptors located in the LC region. |
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Authors:
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L A De Luca; C R Franci; W A Saad; L A Camargo; J Antunes-Rodrigues |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Physiology & behavior Volume: 47 ISSN: 0031-9384 ISO Abbreviation: Physiol. Behav. Publication Date: 1990 Apr |
Date Detail:
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Created Date: 1990-09-20 Completed Date: 1990-09-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0151504 Medline TA: Physiol Behav Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 605-10 Citation Subset: IM |
Affiliation:
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Department of Physiology, School of Medicine, University of São Paulo, Brazil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / physiology Brain Mapping Cholinergic Fibers / physiology* Locus Coeruleus / physiology* Male Natriuresis / physiology* Neurons / physiology Potassium / urine* Rats Rats, Inbred Strains Receptors, Cholinergic / physiology Water-Electrolyte Balance / physiology* |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Cholinergic; 7440-09-7/Potassium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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