Document Detail


The National Cholesterol Education program: guidelines and commentaries.
MedLine Citation:
PMID:  2076138     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is overwhelming evidence that atherosclerosis is caused by elevated cholesterol levels and that the process can be prevented, arrested, and even reversed by altering the cholesterol fractions. The National Cholesterol Education program established guidelines for the management of hypercholesterolemia. Classification of cholesterol values are: Desirable 200 mg./dl, Borderline high 200-239 mg./dl high risk 240 mg./dl and above. Total cholesterol is used for case finding and screening, but LDL cholesterol is the key index for decisions requiring treatment. Classification of LDL levels is as follows: High risk 160 mg/.dl and over, Borderline 130 to 159 mg./dl, Acceptable 130 mg./dl and below. Secondary and familiar disorders should be identified. Dietary therapy is the cornerstone of cholesterol reducing interventions. Steps one and two diets are described, with limitations of saturated fats to 10% of total calories and cholesterol to 300 mg./daily in step one; step two diet limits saturated fats to 7% of total calories-and cholesterol to 200 mg./daily. Pharmacotherapy is based on 5 groups of hypolipidemics agents: A--Resins (cholestyramine and colestipol) B--Nicotinic acid C--Probucol D--Fibric acids (gemfibrozil) E--Reductase inhibitors (lovastatin). Some areas of criticism and controversies regarding the guidelines are discussed and identified.
Authors:
A Zerbi
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Publication Detail:
Type:  Guideline; Journal Article; Review    
Journal Detail:
Title:  Boletín de la Asociación Médica de Puerto Rico     Volume:  82     ISSN:  0004-4849     ISO Abbreviation:  Bol Asoc Med P R     Publication Date:  1990 Nov 
Date Detail:
Created Date:  1991-04-22     Completed Date:  1991-04-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7505267     Medline TA:  Bol Asoc Med P R     Country:  PUERTO RICO    
Other Details:
Languages:  eng     Pagination:  491-5     Citation Subset:  IM    
Affiliation:
Department of Medicine, San Pablo Medical Center, Bayamón, Puerto Rico.
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MeSH Terms
Descriptor/Qualifier:
Humans
Hypercholesterolemia / therapy*
Patient Education as Topic / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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