Document Detail

Nasopharyngeal pH monitoring in chronic sinusitis patients using a novel four channel probe.
MedLine Citation:
PMID:  15475786     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the prevalence of acid reflux into the nasopharynx in patients with chronic sinusitis. STUDY DESIGN: Prospective study of patients presenting to a specialist rhinology practice with chronic sinusitis. METHODS: Forty patients with chronic sinusitis underwent ambulatory 24 hour pH testing. The mean age of the patients was 56.3 years (25 Female, 15 Male). The studies were performed using a specially developed bifurcated 4 channel pH probe, incorporating 2 circumferential sensors positioned at the naso- and hypo-pharynx, and 2 unidirectional sensors positioned at the proximal and distal esophagus. RESULTS: The circumferential band sensors yielded a stable recording largely free of artefact allowing meaningful recordings to be obtained from thirty-seven patients. Twelve patients (32.4%) were diagnosed with gastroesophageal reflux. A total of 809 reflux episodes were recorded. Of these, 596 (73.7%) reached the distal esophagus, with 187 (23.1%) and 24 (3.0%) reaching the proximal esophagus and hypopharynx respectively. Only 2 episodes (0.2%) were recorded in the nasopharynx. This occurred in 2 of 37 patients (5%). CONCLUSIONS: Acid reflux into the nasopharynx is a rare event in patients with chronic sinusitis even though a significant proportion (32.4%) have abnormal 24 hour pH studies. It is likely that alternative mechanisms other than direct acid contact are involved in the pathogenesis of chronic sinusitis.
I W Y Wong; T I Omari; J C Myers; G Rees; S B Nair; G G Jamieson; P J Wormald
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Laryngoscope     Volume:  114     ISSN:  0023-852X     ISO Abbreviation:  Laryngoscope     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-10-11     Completed Date:  2004-10-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1582-5     Citation Subset:  IM    
Department of Surgery--Otolaryngology, Head and Neck Surgery, Adelaide and Flinders Universities, South Australia.
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MeSH Terms
Chronic Disease
Gastric Acidity Determination / instrumentation*
Gastroesophageal Reflux / complications*,  diagnosis
Middle Aged
Monitoring, Ambulatory / instrumentation*
Prospective Studies
Reproducibility of Results
Risk Factors
Signal Processing, Computer-Assisted / instrumentation*
Sinusitis / diagnosis,  etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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