Document Detail


Nasopharyngeal carcinoma with splenic and cystic liver metastases in a pediatric patient: 18F-FDG PET-CT findings.
MedLine Citation:
PMID:  20922367     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Pediatric nasopharyngeal carcinoma (NPC) is rare and usually poorly differentiated. We report a 14-year-old boy with NPC with metastases to liver, spleen, lymph nodes and bone marrow. The liver metastases closely resembled benign cystic liver disease on imaging; however, they showed intense uptake similar to other metastatic sites on positron emission tomography (PET) scan. A liver biopsy could not be performed on the boy. The boy responded clinically to platinum-based chemotherapy, and all the baseline PET-positive lesions became negative. This case highlights the rarity of splenic and cystic liver metastases in pediatric NPC and demonstrates the potential use of PET/CT in diagnosis, staging and response assessment in metastatic pediatric NPC.
Authors:
Venkatraman Radhakrishnan; Sanjay Thulkar; Sellam Karunanithi; Nadeem Tanveer; Sameer Bakhshi
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Publication Detail:
Type:  Journal Article     Date:  2010-10-05
Journal Detail:
Title:  Pediatric radiology     Volume:  40 Suppl 1     ISSN:  1432-1998     ISO Abbreviation:  Pediatr Radiol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365332     Medline TA:  Pediatr Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  S79-82     Citation Subset:  IM    
Affiliation:
Department of Medical Oncology, Dr. B. R. A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, 110029, India.
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