Document Detail

Nasopharyngeal carcinoma in young patients.
MedLine Citation:
PMID:  2337878     Owner:  NLM     Status:  MEDLINE    
Seventy-one Chinese patients ranging in age from 9 to 20 years who had histologically verified nasopharyngeal carcinoma were reviewed. The presenting symptoms were often multiple, comprising nasal (77.5%) and ear (73.2%) symptoms, headache (60.6%), and neck swelling (63.4%). The median duration of these symptoms was 2 to 3 months, and 90.1% of the patients were Stage III or IV at presentation. All patients were treated primarily by radiotherapy. Forty-four of the 71 patients died of the disease; the median time to death was 18 months. Nasopharyngeal carcinoma in the young patients in Hong Kong does not appear to be different from that of the adult population in Hong Kong in terms of histology, pattern of relapse, and survival. Compared with the adult patients, however, the current series of young patients presented with more advanced-staged disease. The incidence of nasopharyngeal carcinoma in Hong Kong was compared with Chinese populations in other parts of the world, and the general pattern was comparable. The only postadolescent peak was found in the Chinese population of San Francisco.
J S Sham; Y F Poon; W I Wei; D Choy
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer     Volume:  65     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-06-20     Completed Date:  1990-06-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2606-10     Citation Subset:  AIM; IM    
Institute of Radiotherapy and Oncology, Queen Mary Hospital, Hong Kong.
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MeSH Terms
Age Factors
Hong Kong / epidemiology
Nasopharyngeal Neoplasms / epidemiology*,  mortality,  therapy
Neoplasm Recurrence, Local
Survival Rate

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