Document Detail


Nasopharyngeal amyloidosis: an unusual cause for epistaxis.
MedLine Citation:
PMID:  19527533     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: We report the first case of nasal and nasopharyngeal amyloidosis secondary to multiple myeloma; this case also represents the fourth report of systemic nasal or nasopharyngeal amyloidosis. METHOD: Case report and review of the world literature concerning nasal and nasopharyngeal amyloidosis epidemiology, presentation and management. RESULTS: Nasal and nasopharyngeal amyloidosis is rare. The presentation, clinical course and treatment are discussed for the presented patient. The amyloid tumour, which recurred in correlation with the progressive transformation of the multiple myeloma, was treated surgically. Subsequent localised radiotherapy decreased the size and growth rate of the tumour. CONCLUSION: Amyloid should be considered as a cause of resistant or recurrent epistaxis provided a mass lesion is seen on radiological imaging. Radiotherapy may be a treatment option in nasal and nasopharyngeal amyloidosis.
Authors:
M A Oluk; J Murphy
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-06-16
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  124     ISSN:  1748-5460     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-27     Completed Date:  2010-05-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  209-12     Citation Subset:  AIM; IM    
Affiliation:
Department of Haematology, West Wales General Hospital, Carmarthen, Wales, UK. Oluk2000@hotmail.co.uk
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MeSH Terms
Descriptor/Qualifier:
Amyloidosis / complications*,  diagnosis*,  therapy
Epistaxis / etiology*
Humans
Male
Middle Aged
Multiple Myeloma / complications*
Nasopharyngeal Diseases / complications*,  diagnosis,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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