| Nasopharyngeal adenoid cystic carcinoma: magnetic resonance imaging features in ten cases. | |
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MedLine Citation:
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PMID: 22200180 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Nasopharyngeal adenoid cystic carcinoma (NACC) is a rare malignancy with high local invasiveness. To date, there is no clear consensus on the imaging characteristics of NACC. To address this, we retrospectively reviewed 10 cases of NACC and summarized the magnetic resonance imaging (MRI) features. Magnetic resonance images of 10 patients with histologically validated NACC were reviewed by two experienced radiologists. The locations, shapes, margins, signal intensity, lesion texture, contrast enhancement patterns, local invasion, and cervical lymphadenopathy of all tumors were evaluated. Clinical and pathological records were also reviewed. None of the patients tested positive for antibodies against Epstein-Barr virus (EBV). The imaging patterns of primary tumors were classified into two types as determined by location, shape, and margins. Of all patients, 7 had tumors with a type 1 imaging pattern and 3 had tumors with a type 2 imaging pattern. The 4 tubular NACCs were all homogeneous tumors, whereas 3 (60%) of 5 cribriform NACCs and the sole solid NACC were heterogeneous tumors with separations or central necrosis within the lesions on MR images. A total of 5 patients had perineural infiltration and intracranial involvement, and only 2 patients had cervical lymphadenopathy. Based on these results, we conclude that NACC is a local, aggressive neoplasm that is often associated with negative laboratory test results for EBV infection and a low incidence of cervical lymphadenopathy. Furthermore, MRI features of NACC vary in different locations and histiological subtypes. |
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Authors:
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Xue-Wen Liu; Chuan-Miao Xie; Hui Li; Rong Zhang; Zhi-Jun Geng; Yun-Xian Mo; Jing Zhao; Mu-Yan Cai; Yan-Chun Lv; Pei-Hong Wu |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-23 |
Journal Detail:
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Title: Chinese journal of cancer Volume: - ISSN: 1944-446X ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-27 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101498232 Medline TA: Chin J Cancer Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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State Key Laboratory of Oncology in South China;Medical Imaging and Minimally Invasive Interventional Center, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China wuph@sysucc.org.cn. |
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