Document Detail

Nasal transit time in normal subjects and pathologic conditions.
MedLine Citation:
PMID:  2126124     Owner:  NLM     Status:  MEDLINE    
A radionuclide method using Tc-99m was used to measure the nasal transit time in 43 patients, including normal smokers and nonsmokers and those with various nasal or paranasal pathologies. The technique described was slightly modified from that already in use in various centers in order to enable more precise measurement. Measurement of transit time of a droplet of Tc-99m phytate on the nasal mucosa appears to differentiate patients with immotile cilia syndrome from normal controls. A positive test, however, can occur also in smokers and in patients with other nasal and paranasal problems. The test is reproducible, cost-effective, and noninvasive, enabling the clinician to make a more appropriate selection of patients needing further investigation.
M Englender; D Chamovitz; M Harell
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  103     ISSN:  0194-5998     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  1990 Dec 
Date Detail:
Created Date:  1991-03-01     Completed Date:  1991-03-01     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  909-12     Citation Subset:  IM    
Department of Pediatric Otolaryngology, Edith Wolfson Hospital, Holon, Israel.
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MeSH Terms
Ciliary Motility Disorders / radionuclide imaging*
Middle Aged
Mucociliary Clearance / physiology*
Nasal Mucosa / physiopathology,  radionuclide imaging*
Nose Diseases / physiopathology,  radionuclide imaging*
Organotechnetium Compounds / diagnostic use
Paranasal Sinus Diseases / physiopathology,  radionuclide imaging*
Phytic Acid / diagnostic use
Smoking* / physiopathology
Time Factors
Reg. No./Substance:
0/Organotechnetium Compounds; 0/technetium phytate; 83-86-3/Phytic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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