Document Detail


Nasal ketamine for paediatric premedication.
MedLine Citation:
PMID:  8443849     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ketamine in a dose of 6 mg.kg-1 was nasally administered in 86 healthy children (ASA I and II), aged from two to five years undergoing elective general, urological or plastic surgery, 20 to 40 min before the scheduled surgery time. These children were compared with 62 others, also aged from two to five years, in whom promethazine and meperidine, 1 mg.kg-1 of each, were injected im. Sedation was started as excellent in 48 and as adequate in 19 children in the ketamine group, compared with nine and 12 respectively in Group 2 (P < 0.05), while salivation was similar in both groups. We conclude that nasal ketamine is an alternative to im preanaesthetic sedation administration in children aged from two to five years.
Authors:
N Weksler; L Ovadia; G Muati; A Stav
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Canadian journal of anaesthesia = Journal canadien d'anesthésie     Volume:  40     ISSN:  0832-610X     ISO Abbreviation:  Can J Anaesth     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1993-04-05     Completed Date:  1993-04-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701709     Medline TA:  Can J Anaesth     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  119-21     Citation Subset:  IM    
Affiliation:
Department of Anaesthesia, Hillel Yaffe Medical Center, Hadera, Israel.
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MeSH Terms
Descriptor/Qualifier:
Administration, Intranasal
Anesthesia Recovery Period
Anesthesia, Inhalation
Child, Preschool
Conscious Sedation*
Double-Blind Method
Female
Humans
Injections, Intramuscular
Ketamine / administration & dosage,  therapeutic use*
Male
Meperidine / administration & dosage,  therapeutic use
Preanesthetic Medication*
Promethazine / administration & dosage,  therapeutic use
Salivation / drug effects
Time Factors
Chemical
Reg. No./Substance:
57-42-1/Meperidine; 60-87-7/Promethazine; 6740-88-1/Ketamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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