| Nasal intermittent positive pressure ventilation. Long-term follow-up in patients with severe chronic respiratory insufficiency. | |
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MedLine Citation:
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PMID: 8275718 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Prior studies have shown that nasal intermittent positive pressure ventilation (NIPPV) can improve arterial blood gas values, prevent symptoms resulting from alveolar hypoventilation, and decrease hospitalization in patients with chronic respiratory failure. Most studies have involved small samples of patients followed up for a limited time. This study reviews our experience during 5 years use of NIPPV in 276 patients with kyphoscoliosis, posttuberculosis sequelae, Duchenne-type muscular dystrophy, COPD, and bronchiectasis followed up for > or = 3 years while receiving NIPPV. Outcomes were compared for patients who survived short term eg, died or converted to management with a tracheostomy and intermittent positive ventilation (TIPPV) during year 1 or year 2 on a regimen of NIPPV and long term, eg, survived more > or = 2 years on a regimen of NIPPV. The most favorable outcome was achieved by patients with kyphoscoliosis and posttuberculosis sequelae with improvement in PaO2 and PaCO2 (p < 0.0001) and a reduction in days of hospitalization for respiratory illness (p < 0.0001) for > or = 2 years while receiving NIPPV. Patients with Duchenne-type muscular dystrophy also had fewer hospital days during NIPPV (p < 0.003) but only 9 of 16 patients (56 percent) continued using NIPPV for the duration of followup. Benefit was also more short term for patients with COPD and bronchiectasis. NIPPV can sustain improvement in gas exchange, while reducing hospitalization for substantial periods of time. NIPPV can be an attractive and effective alternative to other methods of assisted ventilation such as TIPPV. |
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Authors:
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P Leger; J M Bedicam; A Cornette; O Reybet-Degat; B Langevin; J M Polu; L Jeannin; D Robert |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chest Volume: 105 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1994 Jan |
Date Detail:
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Created Date: 1994-02-10 Completed Date: 1994-02-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 100-5 Citation Subset: AIM; IM |
Affiliation:
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Service de Reanimation et Assistance Respiratoire Hopital de la Croix-Rousse, Lyon, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bronchiectasis / complications, physiopathology Carbon Dioxide / blood Chronic Disease Female Follow-Up Studies Forced Expiratory Volume / physiology Hospitalization Humans Intermittent Positive-Pressure Ventilation / instrumentation, methods* Kyphosis / complications, physiopathology Lung Diseases, Obstructive / complications, physiopathology Male Masks Middle Aged Muscular Dystrophies / complications, physiopathology Oxygen / blood Respiratory Insufficiency / blood, etiology, physiopathology, therapy* Scoliosis / complications, physiopathology Survival Rate Tidal Volume / physiology Tracheostomy Treatment Outcome Tuberculosis, Pulmonary / complications, physiopathology Vital Capacity / physiology |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
| Comments/Corrections | |
Comment In:
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Chest. 1995 Feb;107(2):592
[PMID:
7842813
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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