Document Detail

Nasal histamine reactivity in woodwork teachers.
MedLine Citation:
PMID:  11072656     Owner:  NLM     Status:  MEDLINE    
Woodworkers exposed to wood dust have an increased frequency of rhinitis. We have previously reported such rhinitis in woodwork teachers. To test whether their nasal complaints are related to nasal hyper-reactivity, we selected 14 woodwork teachers with work-related rhinitis and 14 healthy and non-allergic control persons for nasal histamine challenge using symptom scores (0-3 scale) and acoustic rhinometry for effect evaluation. Intranasal saline followed by doubled concentrations of histamine phosphate (from 0.062 to 16 mg/ml) was given at five-minute intervals. There was no significant difference between the groups regarding symptom scores or acoustic rhinometry during the challenge. The results indicate that nasal hyperreactivity is not a prominent factor in wood-dust-related rhinitis. Other mechanisms probably prompt the nasal complaints.
M Ahman; M Holmström
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Rhinology     Volume:  38     ISSN:  0300-0729     ISO Abbreviation:  Rhinology     Publication Date:  2000 Sep 
Date Detail:
Created Date:  2001-02-23     Completed Date:  2001-03-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0347242     Medline TA:  Rhinology     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  114-9     Citation Subset:  IM    
Department of Occupational Health, Stockholm, Sweden.
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MeSH Terms
Histamine / diagnostic use*
Middle Aged
Nasal Provocation Tests / methods*
Occupational Diseases / diagnosis*
Respiratory Hypersensitivity / diagnosis*
Rhinitis, Allergic, Perennial / diagnosis*
Reg. No./Substance:
0/Dust; 51-45-6/Histamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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