Document Detail

Nasal fibrosis: long-term follow up of four cases of eosinophilic angiocentric fibrosis.
MedLine Citation:
PMID:  15829064     Owner:  NLM     Status:  MEDLINE    
Eosinophilic angiocentric fibrosis is a rare, benign cause of submucosal thickening and fibrosis within the upper respiratory tract. It predominantly affects the nose although cases have been reported in the subglottis. We describe four cases of the disease centred around the nasal cavity, with widespread infiltration of the facial soft tissues and orbit in three of the four patients. Each underwent long term follow up. Multiple surgical resections were required with two of our patients and, to date, medical therapy has been of limited help. The disease process, with its clinical and characteristic histopathological findings, is described. We also discuss the management of the disease following a comprehensive review of, and comparison with, the few prior reported cases.
Santdeep Paun; Valerie J Lund; Andrew Gallimore
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  119     ISSN:  0022-2151     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-04-14     Completed Date:  2005-06-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  119-24     Citation Subset:  AIM; IM    
Royal National Throat, Nose and Ear Hospital, London, UK.
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MeSH Terms
Eosinophilia / diagnosis*,  pathology,  radiography
Magnetic Resonance Imaging
Middle Aged
Nasal Cavity / pathology*,  radiography
Nasal Obstruction / etiology*,  pathology,  radiography
Tomography, X-Ray Computed

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