Document Detail

Nasal cuboidal metaplasia with dysplasia. Precursor to adenocarcinoma in wood-dust-exposed workers?
MedLine Citation:
PMID:  4024915     Owner:  NLM     Status:  MEDLINE    
The histological study of the non-tumours nasal mucosa in 22 wood-workers with ethmoidal adenocarcinoma was carried out and special attention was paid to the presence of cuboidal metaplasia with or without dysplasia. The workers had been exposed to wood dust for an average of 38 years (range 18 to 55 years). In 19 cases cuboidal metaplasia was found and 16 of these also had dysplasia. In 10 cases there was a transitional zone with dysplastic cuboidal epithelium in continuity with the tumour. In 5 cases there was squamous metaplasia. The results indicate cuboidal metaplasia with dysplasia being a possible precursor to nasal adenocarcinoma in workers exposed to wood dust, similar to the findings of squamous metaplasia and squamous cell carcinoma in nickel workers.
B Wilhelmsson; H Hellquist; J Olofsson; C Klintenberg
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  99     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:    1985 May-Jun
Date Detail:
Created Date:  1985-09-04     Completed Date:  1985-09-04     Revised Date:  2006-04-19    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  641-8     Citation Subset:  IM    
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MeSH Terms
Adenocarcinoma / etiology
Adenocarcinoma, Papillary / pathology*
Middle Aged
Nasal Mucosa / pathology*
Nose Neoplasms / etiology,  pathology*
Occupational Diseases / etiology
Precancerous Conditions / pathology*
Reg. No./Substance:

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