| Nasal cuboidal metaplasia with dysplasia. Precursor to adenocarcinoma in wood-dust-exposed workers? | |
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MedLine Citation:
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PMID: 4024915 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The histological study of the non-tumours nasal mucosa in 22 wood-workers with ethmoidal adenocarcinoma was carried out and special attention was paid to the presence of cuboidal metaplasia with or without dysplasia. The workers had been exposed to wood dust for an average of 38 years (range 18 to 55 years). In 19 cases cuboidal metaplasia was found and 16 of these also had dysplasia. In 10 cases there was a transitional zone with dysplastic cuboidal epithelium in continuity with the tumour. In 5 cases there was squamous metaplasia. The results indicate cuboidal metaplasia with dysplasia being a possible precursor to nasal adenocarcinoma in workers exposed to wood dust, similar to the findings of squamous metaplasia and squamous cell carcinoma in nickel workers. |
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Authors:
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B Wilhelmsson; H Hellquist; J Olofsson; C Klintenberg |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta oto-laryngologica Volume: 99 ISSN: 0001-6489 ISO Abbreviation: Acta Otolaryngol. Publication Date: 1985 May-Jun |
Date Detail:
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Created Date: 1985-09-04 Completed Date: 1985-09-04 Revised Date: 2006-04-19 |
Medline Journal Info:
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Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 641-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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etiology Adenocarcinoma, Papillary / pathology* Adolescent Adult Dust Humans Male Metaplasia Middle Aged Nasal Mucosa / pathology* Nose Neoplasms / etiology, pathology* Occupational Diseases / etiology Precancerous Conditions / pathology* Wood* |
| Chemical | |
Reg. No./Substance:
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0/Dust |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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