| Nasal bilevel vs. continuous positive airway pressure in preterm infants. | |
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MedLine Citation:
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PMID: 16155882 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Our aim was to compare the effects of nasal bilevel positive airway pressure (N-BiPAP) and nasal continuous positive airway pressure (N-CPAP) on gas exchange in preterm babies. Twenty preterm infants (mean gestational age, 26.3 weeks; mean weight at study, 1,033 g) were evaluated. Patients received two repeated cycles of N-CPAP alternated with N-BiPAP, for a total of four alternated phases, each phase lasting 1 hr. Transcutaneous PO2 (TcPO2), transcutaneous PCO2 (tcPCO2), pulsoximetry, and respiratory rate were recorded every 15 min. Arterial blood gases and acid-base balance were measured at the beginning of the first study period on baseline CPAP and at the end of the last study period on bilevel positive airway pressure. During the two N-BiPAP phases, a statistically significant (P < 0.001) increase of peripheral oxygen saturation and tcPO2, and a significant (P < 0.001) reduction of tcPCO2 and respiratory rate, were noted as compared to the two N-CPAP periods. In addition, a significant improvement of PO2 (P < 0.003) and a reduction of PCO2 were noted at the end of the test (P < 0.02). In conclusion, N-BiPAP, as compared to N-CPAP, improved gas exchange in preterm infants. |
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Authors:
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Claudio Migliori; Mario Motta; Agnese Angeli; Gaetano Chirico |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Pediatric pulmonology Volume: 40 ISSN: 8755-6863 ISO Abbreviation: Pediatr. Pulmonol. Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-10-03 Completed Date: 2006-03-16 Revised Date: 2006-03-28 |
Medline Journal Info:
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Nlm Unique ID: 8510590 Medline TA: Pediatr Pulmonol Country: United States |
Other Details:
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Languages: eng Pagination: 426-30 Citation Subset: IM |
Copyright Information:
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(c) 2005 Wiley-Liss, Inc. |
Affiliation:
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Division of Neonatology and Neonatal Intensive Care Unit, Spedali Civili, Brescia, Italy. claudio.migliori@tin.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Gas Analysis Carbon Dioxide / blood Continuous Positive Airway Pressure* Cross-Over Studies Female Humans Infant, Newborn Infant, Premature Male Oxygen / blood Positive-Pressure Respiration / methods* Pulmonary Gas Exchange Respiratory Distress Syndrome, Newborn / therapy* Respiratory Mechanics |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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