| Nasal architecture: form and flow. | |
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MedLine Citation:
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PMID: 18593666 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Current approaches to model nasal airflow are reviewed in this study, and new findings presented. These new results make use of improvements to computational and experimental techniques and resources, which now allow key dynamical features to be investigated, and offer rational procedures to relate variations in anatomical form. Specifically, both replica and simplified airways of a single subject were investigated and compared with the replica airways of two other individuals with overtly differing geometries. Procedures to characterize and compare complex nasal airway geometry are first outlined. It is then shown that coupled computational and experimental studies, capable of obtaining highly resolved data, reveal internal flow structures in both intrinsically steady and unsteady situations. The results presented demonstrate that the intimate relation between nasal form and flow can be explored in greater detail than hitherto possible. By outlining means to compare complex airway geometries and demonstrating the effects of rational geometric simplification on the flow structure, this work offers a fresh approach to studies of how natural conduits guide and control flow. The concepts and tools address issues that are thus generic to flow studies in other physiological systems. |
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Authors:
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D J Doorly; D J Taylor; A M Gambaruto; R C Schroter; N Tolley |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Philosophical transactions. Series A, Mathematical, physical, and engineering sciences Volume: 366 ISSN: 1364-503X ISO Abbreviation: Philos Transact A Math Phys Eng Sci Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-11 Completed Date: 2008-10-17 Revised Date: 2011-02-28 |
Medline Journal Info:
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Nlm Unique ID: 101133385 Medline TA: Philos Transact A Math Phys Eng Sci Country: England |
Other Details:
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Languages: eng Pagination: 3225-46 Citation Subset: IM |
Affiliation:
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Department of Aeronautics, Imperial College London, London SW7 2AZ, UK. d.doorly@imperial.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Computer Graphics Computer Simulation Humans Models, Anatomic* Models, Biological* Nose / anatomy & histology*, physiology* Pulmonary Ventilation / physiology* Respiration* Rheology / methods* |
| Grant Support | |
ID/Acronym/Agency:
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BB/E023444/1//Biotechnology and Biological Sciences Research Council; BBE0234441//Biotechnology and Biological Sciences Research Council; BBE18557//Biotechnology and Biological Sciences Research Council |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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