Document Detail

Nasal airway dimensions and lung function in awake, healthy neonates.
MedLine Citation:
PMID:  9516093     Owner:  NLM     Status:  MEDLINE    
Possible relations between nasal airway dimensions and measures of lung function are not well established. It has been suggested that a major part of airway resistance is found in the nose. However, little is known about the shape of tidal flow volume (TFV) loops in relation to nasal caliber. We therefore investigated whether lung function assessed by tidal breathing in healthy newborn infants was affected by nasal airway dimensions. Nasal airway dimensions were measured in 17 healthy newborn babies (mean age, 2.7 days) by acoustic rhinometry before and immediately after lung function measurements. Lung function was evaluated by TFV loops and passive respiratory mechanics (single-breath occlusion technique), first with both nostrils open, and subsequently immediately after occlusion of the larger of the two nostrils, causing at least a 50% reduction in nasal minimum cross-sectional area (MCA). Neither the TFV expiratory ratios (time and volume to reach peak flow to total time and volume, respectively [t(PTEF)/t(E) and V(PTEF)/V(E), respectively]), nor resistance or compliance of the total respiratory system differed significantly regardless of whether one or both nostrils were open. With one nostril closed there were no significant effects on any of the measured lung function parameters. We conclude that in healthy awake neonates reducing the cross-sectional area of nasal dimensions by 50% does not affect TFV loops or passive respiratory mechanics.
P G Djupesland; K C Lødrup Carlsen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  25     ISSN:  8755-6863     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-05-07     Completed Date:  1998-05-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  99-106     Citation Subset:  IM    
Department of Otorhinolaryngology, Ullevaal University Hospital, Oslo, Norway.
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MeSH Terms
Infant, Newborn / physiology*
Nasal Cavity / anatomy & histology*,  physiology
Reference Values
Respiratory Mechanics*
Tidal Volume

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