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Nasal Polyposis: An Overview of Differential Diagnosis and Treatment.
MedLine Citation:
PMID:  21834752     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Osmangazi University, Medical Faculty, Department of Otorhinolaryngology, Eskisehir, Turkey. Nasal polyposis is a chronic inflammatory disease of the nasal and paranasal sinus mucosa. Etiology remains unclear, but allergy, asthma, aspirin sensitivity, cystic fibrosis, and infection have been associated with the disease. Clinically, nasal obstruction, anosmia/hyposmia, rhinorrhea, postnasal drainage, headaches, facial pain, and sleep disorders constitute the main symptoms. Intranasal examination reveals bilateral, mobile, grey, smooth and semi translucent polypoid masses that usually originate in the ethmoid sinuses or the middle meatus. Differential diagnosis is important to rule out congenital anomalies, as well as benign or malignant tumors. In the evaluation of nasal polyps, computerized tomography is helpful especially in determining the extent of the disease and in planning the surgical approach. Management of nasal polyposis consists of medical therapy and surgery. Surgical treatment is performed in cases that are refractory to medical therapy. Recurrence of nasal polyps is quite common and medical therapy after surgery is often necessary for avoiding recurrences. This paper aims to summarize the current trends in the diagnosis, management of nasal polyposis and relevant patents.
Authors:
Cemal Cingi; Duygu Demirbas; Ahmet Ural
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-12
Journal Detail:
Title:  Recent patents on inflammation & allergy drug discovery     Volume:  -     ISSN:  1872-213X     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101309297     Medline TA:  Recent Pat Inflamm Allergy Drug Discov     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Medical Faculty, Department of Otorhinolaryngology Karadeniz Technical University, Trabzon, Turkey. ahmetural2001@yahoo.com.
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