Document Detail

Nasal Colonization among Premature Infants Treated with Nasal Continuous Positive Airway Pressure.
MedLine Citation:
PMID:  21117015     Owner:  NLM     Status:  In-Data-Review    
We examined the relationship between the use of nasal continuous positive airway pressure (CPAP) and nasal colonization among low-birth-weight (LBW) infants. We prospectively cultured the nares of LBW infants on admission and weekly until hospital discharge. The modality of respiratory support during each culture was recorded. Bivariate and multivariate analyses were conducted to test the relationship between CPAP and nasal colonization. Analyses were repeated after stratifying infants into three birth-weight categories: 1500 to 2499 g, 1000 to 1499 g, and < 1000 g. In total, 766 nasal cultures were obtained from 167 infants. Nasal colonization with gram-negative bacilli was increased with the use of CPAP in all birth-weight categories ( P < 0.05) and with vaginal delivery in infants weighing < 1000 g and 1500 to 2499 g ( P = 0.04 and P = 0.02, respectively). Nasal colonization with any potential pathogen increased with the use of CPAP in all birth-weight categories ( P < 0.001), with the presence of chorioamnionitis in infants < 1000 g ( P = 0.055) and at younger gestational age in infants 1000 to 1499 g ( P = 0.0026). Caucasian infants 1500 to 2499 g had less colonization than infants of other races ( P = 0.01). Nasal CPAP is associated with increased colonization with gram-negative bacilli.
Hany Aly; Tarek A Hammad; Maide Ozen; Inderjeet Sandhu; Chita Taylor; Adenike Olaode; Mohamed Mohamed; John Keiser
Related Documents :
16503785 - Survivorship and mortality implications of developmental 670-nm phototherapy: dioxin co...
3785975 - In vitro demonstration of in utero larval development in an oviparous parasitic nematod...
22282155 - Relationship of neonatal treatments with the development of necrotizing enterocolitis i...
24637795 - Early life establishment of site-specific microbial communities in the gut.
9105795 - Maternal tobacco smoke exposure and persistent pulmonary hypertension of the newborn.
10736085 - Traumatic pharyngo-oesophageal perforation in the newborn: a condition mimicking oesoph...
Publication Detail:
Type:  Journal Article     Date:  2010-11-29
Journal Detail:
Title:  American journal of perinatology     Volume:  28     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  315-20     Citation Subset:  IM    
Copyright Information:
© Thieme Medical Publishers.
Department of Newborn Services, the George Washington University and Children's National Medical Center, Washington, DC.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  One hundred consecutive infants born at 23 weeks and resuscitated.
Next Document:  [Preservative-free triamcinolone versus purified triamcinolone preparations].