Document Detail


Nasal CPAP (Infant Flow) applied at birth in extremely low birth weight newborns.
MedLine Citation:
PMID:  25182261     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: Evaluation of nasal CPAP (Infant Flow) as a ventilatory support, applied at birth in spontaneously breathing, extremely low birth weight newborns (ELBW).
MATERIAL AND METHODS: Retrospective analysis of the clinical course of respiratory distress syndrome (RDS) in 97 ELBW, who needed ventilatory support. In all patients the noninvasive ventilatory support was introduced within the first minute of life.
RESULTS: Among all analyzed newborns, 37.1% of patients were not intubated during hospitalization. Moreover, another 10.3% patients were intubated only due to surfactant administration according to the INSURE method and after 2-3 minutes of invasive ventilation they were switched to n-CPAP. Nearly half (47.4%) of all evaluated ELBW newborns who needed ventilatory support avoided mechanical ventilation. We found the frequency of bronchopulmonary dysplasia in 97 analyzed patients markedly lower when compared to data presented in literature (19% vs 34%; p=0.026).
CONCLUSION: We suggest that starting ventilatory support with the n-CPAP from the first minute of life is a safe and effective strategy in extremely low birth weight infants. It also reduces the costs of treatment, associated with surfactant administration.
Authors:
Agnieszka Nowicka; Ryszard Lauterbach
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Developmental period medicine     Volume:  18     ISSN:  1428-345X     ISO Abbreviation:  Dev Period Med     Publication Date:  2014  
Date Detail:
Created Date:  2014-09-03     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101636421     Medline TA:  Dev Period Med     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  216-20     Citation Subset:  IM    
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