| Narrow-band imaging flexible cystoscopy in the detection of recurrent urothelial cancer of the bladder. | |
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MedLine Citation:
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PMID: 18005206 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate whether narrow-band imaging (NBI) flexible cystoscopy improves the detection rate of urothelial carcinomas (UCs) of the bladder. NBI is an optical image enhancement technology in which the narrow bandwidth of light is strongly absorbed by haemoglobin and penetrates only the surface of tissue, increasing the visibility of capillaries and other delicate tissue surface structures by enhancing contrast between the two. PATIENTS AND METHODS: Between November 2005 and May 2007 at the Queen Elizabeth Hospital, Birmingham, NBI flexible cystoscopy was performed on 29 patients with known recurrences of UC of the bladder after initial conventional white-light imaging (WLI) flexible cystoscopy with the same instrument (Olympus Lucera sequential RGB endoscopy system). RESULTS: Subjectively, NBI provided a much clearer view of bladder UCs and in particular their delicate capillary architecture. Objectively, NBI detected 15 additional UCs in 12 of 29 patients (41%), as compared with WLI. The mean (sd) difference was 0.52 (0.74) UCs per patient (P < 0.001, Wilcoxon signed-rank test). CONCLUSIONS: Even in the few patients studied there is strong evidence that NBI differs from WLI in the number of UCs it detects, with a significantly increased detection rate. We feel that further evaluation of NBI flexible cystoscopy in more patients will show this technique to be highly valuable in the detection of both new and recurrent bladder UCs, and this work is continuing in our unit. |
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Authors:
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Richard T Bryan; Lucinda J Billingham; D Michael A Wallace |
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Publication Detail:
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Type: Journal Article Date: 2007-11-13 |
Journal Detail:
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Title: BJU international Volume: 101 ISSN: 1464-410X ISO Abbreviation: BJU Int. Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-02-22 Completed Date: 2008-03-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100886721 Medline TA: BJU Int Country: England |
Other Details:
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Languages: eng Pagination: 702-5; discussion 705-6 Citation Subset: IM |
Affiliation:
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Department of Public Health and Epidemiology, University of Birmingham, Birmingham, UK. rtb@dsl.pipex.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cystoscopy
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methods* Humans Image Enhancement* Neoplasm Recurrence, Local / diagnosis* Prospective Studies Urinary Bladder / pathology* Urinary Bladder Neoplasms / diagnosis* |
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