Document Detail


Narrow-band UVB (TL-01) phototherapy: an effective preventative treatment for the photodermatoses.
MedLine Citation:
PMID:  7662575     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty patients with photodermatoses [actinic prurigo (n = 6), hydroa vacciniforme (n = 4), idiopathic solar urticaria (n = 1), amiodarone-induced photosensitivity (n = 1) and a range of cutaneous porphyrias (n = 8)] were treated with a 'hardening' course of narrow-band ultraviolet B (TL-01) phototherapy in springtime. The response to phototherapy was monitored subjectively, by interviewing patients after the summer, and objectively by monochromator phototesting, before and after phototherapy. Fifteen patients reported that treatment was worthwhile. Monochromator phototesting after phototherapy revealed a fourfold increase in the minimal erythema dose in those with abnormal photosensitivity to ultraviolet A wavebands. Adverse effects included erythema (seven patients), pruritus (five) and provocation of the eruption (four). We now routinely consider narrow-band UVB phototherapy for problem photodermatoses.
Authors:
P Collins; J Ferguson
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  The British journal of dermatology     Volume:  132     ISSN:  0007-0963     ISO Abbreviation:  Br. J. Dermatol.     Publication Date:  1995 Jun 
Date Detail:
Created Date:  1995-10-10     Completed Date:  1995-10-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0004041     Medline TA:  Br J Dermatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  956-63     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Ninewells Hospital and Medical School, Dundee, U.K.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Amiodarone / adverse effects
Child
Drug Hypersensitivity / prevention & control
Female
Humans
Hydroa Vacciniforme / prevention & control
Male
Middle Aged
Photosensitivity Disorders / prevention & control*
Porphyria, Erythropoietic / prevention & control
Prurigo / prevention & control
Ultraviolet Therapy*
Urticaria / prevention & control
Chemical
Reg. No./Substance:
1951-25-3/Amiodarone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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