Document Detail

Naproxen-associated sudden sensorineural hearing loss.
MedLine Citation:
PMID:  9819544     Owner:  NLM     Status:  MEDLINE    
Naproxen is a commonly used nonsteroidal anti-inflammatory drug (NSAID) whose side effects include tinnitus and transient hearing loss. Sudden sensorineural hearing loss has rarely been reported as a result of NSAID use. This usually occurs in patients taking other ototoxic medications, with poor renal function, or with autoimmune disease. This article reports the case of an otherwise healthy patient who experienced permanent sensorineural hearing loss after a brief course of naproxen and reviews the literature on NSAID-related permanent sensorineural hearing loss.
B J McKinnon; L F Lassen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Military medicine     Volume:  163     ISSN:  0026-4075     ISO Abbreviation:  Mil Med     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1998-12-03     Completed Date:  1998-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2984771R     Medline TA:  Mil Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  792-3     Citation Subset:  IM    
Department of Otolaryngology-Head and Neck Surgery, Naval Medical Center, Portsmouth, VA 23708-2197, USA.
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MeSH Terms
Anti-Inflammatory Agents / therapeutic use
Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
Hearing Loss, Sensorineural / chemically induced*,  diagnosis,  drug therapy
Military Personnel
Naproxen / adverse effects*
Prednisone / therapeutic use
Tinnitus / chemically induced*,  diagnosis,  drug therapy
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Anti-Inflammatory Agents, Non-Steroidal; 22204-53-1/Naproxen; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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