Document Detail

Nap-titration: an effective alternative for continuous positive airway pressure titration.
MedLine Citation:
PMID:  16137873     Owner:  NLM     Status:  MEDLINE    
When treating Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) several alternatives for standard (manual) continuous positive airway pressure (CPAP) titration are feasible. A practical alternative is titration without polysomnography during an afternoon nap (Nap-titration). The aim of the present study was to assess whether Nap-titration is appropriate for effective titration of CPAP. Following Nap-titration 24 eligible OSAHS patients started conventional CPAP therapy. The outcome of Nap-titration was verified after 2 weeks with CPAP pressure adjustments being performed in case of persisting OSAHS symptomatology. Polysomnography and a questionnaire evaluation were performed at baseline and 8 weeks after Nap-titration. Following Nap-titration 15 patients did not require pressure changes while in 9 patients' CPAP pressure was raised due to persisting OSAHS symptomatology. Control polysomnography after 8 weeks showed successful CPAP titration (Apnea-Hypopnea Index <5) in 23 out of 24 patients. A pressure raise following polysomnography was indicated in 1 patient only. In addition, significant improvements were found in OSAHS symptomatology and quality of life. This study shows that in 96% of OSAHS patients' successful CPAP titration is attained following Nap-titration whether or not supplemented by pressure adjustments. Therefore, Nap-titration with an adequate follow-up appears an appropriate procedure for the effective titration of CPAP.
Aarnoud Hoekema; Boudewijn Stegenga; Johannes G van der Aa; Aafke F Meinesz; Johannes H van der Hoeven; Peter J Wijkstra
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-08-30
Journal Detail:
Title:  Respiratory medicine     Volume:  100     ISSN:  0954-6111     ISO Abbreviation:  Respir Med     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-02-28     Completed Date:  2006-10-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8908438     Medline TA:  Respir Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  705-13     Citation Subset:  IM    
Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Hanzeplein 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.
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MeSH Terms
Continuous Positive Airway Pressure / methods*
Middle Aged
Polysomnography / instrumentation
Sleep Apnea, Obstructive / therapy*
Sleep, REM / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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