| Nanotechnology and nanomedicine: going small means aiming big. | |
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MedLine Citation:
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PMID: 20222866 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nanotechnology is an emerging branch of science for designing tools and devices of size 1 to 100 nm with specific function at the cellular, atomic and molecular levels. The concept of employing nanotechnology in biomedical research and clinical practice is best known as nanomedicine. Nanomedicine is an upcoming field that could potentially make a major impact to human health. Nanomaterials are increasingly used in diagnostics, imaging and targeted drug delivery. Nanotechnology will assist the integration of diagnostics/imaging with therapeutics and facilitates the development of personalized medicine, i.e. prescription of specific medications best suited for an individual. This review provides an integrated overview of application of nanotechnology based molecular diagnostics and drug delivery in the development of nanomedicine and ultimately personalized medicine. Finally, we identify critical gaps in our knowledge of nanoparticle toxicity and how these gaps need to be evaluated to enable nanotechnology to transit safely from bench to bedside. |
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Authors:
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Mahesh Kumar Teli; Srinivas Mutalik; G K Rajanikant |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current pharmaceutical design Volume: 16 ISSN: 1873-4286 ISO Abbreviation: Curr. Pharm. Des. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-07-02 Completed Date: 2011-01-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9602487 Medline TA: Curr Pharm Des Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1882-92 Citation Subset: IM |
Affiliation:
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School of Biotechnology, National Institute of Technology Calicut, Calicut, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Drug Delivery Systems / trends Drug Design* Humans Individualized Medicine Nanomedicine / methods, trends* Nanoparticles / adverse effects, diagnostic use, therapeutic use Nanotechnology / methods, trends* Pathology, Molecular / trends Technology Transfer* |
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