| Nanosilver as a new generation of nanoproduct in biomedical applications. | |
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MedLine Citation:
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PMID: 20724010 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nanosilver (NS), comprising silver nanoparticles, is attracting interest for a range of biomedical applications owing to its potent antibacterial activity. It has recently been demonstrated that NS has useful anti-inflammatory effects and improves wound healing, which could be exploited in developing better dressings for wounds and burns. The key to its broad-acting and potent antibacterial activity is the multifaceted mechanism by which NS acts on microbes. This is utilized in antibacterial coatings on medical devices to reduce nosocomial infection rates. Many new synthesis methods have emerged and are being evaluated for NS production for medical applications. NS toxicity is also critically discussed to reflect on potential concerns before widespread application in the medical field. |
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Authors:
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Karla Chaloupka; Yogeshkumar Malam; Alexander M Seifalian |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review Date: 2010-08-18 |
Journal Detail:
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Title: Trends in biotechnology Volume: 28 ISSN: 1879-3096 ISO Abbreviation: Trends Biotechnol. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-15 Completed Date: 2011-01-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8310903 Medline TA: Trends Biotechnol Country: England |
Other Details:
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Languages: eng Pagination: 580-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Centre for Nanotechnology & Regenerative Medicine, Division of Surgery & Interventional Science, University College London, London, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Bacterial Agents
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metabolism,
pharmacology,
therapeutic use* Anti-Inflammatory Agents / metabolism, pharmacology, therapeutic use Biotechnology / methods Humans Nanoparticles / therapeutic use* Silver / metabolism, pharmacology, therapeutic use* Wound Healing / physiology |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Anti-Inflammatory Agents; 7440-22-4/Silver |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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